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Cambridge IGCSE Biology 0610: papers, Core and Extended, dates and grades

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IGCSE Biology papers

PaperWho sits itTimeMarksWeight
Paper 1: Multiple Choice (Core)Core45 min4030%
Paper 2: Multiple Choice (Extended)Extended45 min4030%
Paper 3: Theory (Core)Core1 h 15 min8050%
Paper 4: Theory (Extended)Extended1 h 15 min8050%
Paper 5: Practical TestEveryone, or Paper 61 h 15 min4020%
Paper 6: Alternative to PracticalEveryone, or Paper 51 h4020%

The multiple choice papers have 40 four-option questions, and the theory papers are short-answer and structured questions. Paper 5 is a practical test in the lab and Paper 6 is a written paper on the same experimental skills; your school chooses which. This is the 2026 to 2028 syllabus (version 3, August 2026), which Cambridge says has no significant changes affecting teaching.

Core or Extended?

Cambridge says to enter Core if you have studied the Core content or are expected to get D or below, and Extended if you have studied the Core and Supplement content and are expected to get C or above. Core caps you at grade C. Extended adds Supplement content to most topics, for example converting between millimetres and micrometres when you work out the size of a specimen.

IGCSE Biology exam dates 2027

PapersDate (June 2027 series, zone 3)Session
Paper 3 and Paper 4 (Theory)Monday 26 April 2027Afternoon
Paper 5 (Practical) and Paper 6 (Alternative to Practical)Tuesday 11 May 2027Afternoon
Paper 1 and Paper 2 (Multiple Choice)Tuesday 8 June 2027Afternoon

The June 2027 series runs from 26 April to 11 June 2027, so Biology theory opens it. Cambridge publishes a timetable for each zone, so check yours with your exams officer. IGCSE Biology is also sat in November, and in March in India. November 2026 results come out on 14 January 2027.

IGCSE Biology grade thresholds

Your three papers are weighted into a total out of 200. In June 2026, Cambridge set these thresholds for the most common combinations:

Papers taken (June 2026)A*ABCDE
Extended: 21, 41, 61166138110837364
Extended: 21, 41, 51165137109827263
Core: 11, 31, 61n/an/an/a1129681
Core: 11, 31, 51n/an/an/a1119580

Other versions of the papers had different thresholds (for 23, 43, 63 the A* was 169 and the C was 97), and they change every series, so use them as a guide when you mark past papers.

What IGCSE Biology covers

The 2026 to 2028 syllabus has 21 topics:

  • Cells and molecules: characteristics and classification of living organisms, organisation of the organism, movement into and out of cells, biological molecules, enzymes.
  • Plants: plant nutrition and transport in plants.
  • Humans: human nutrition, transport in animals, diseases and immunity, gas exchange, respiration, excretion, coordination and response, drugs, reproduction.
  • Genetics: inheritance, and variation and selection.
  • Ecology and technology: organisms and their environment, human influences on ecosystems, biotechnology and genetic modification.

Worked examples

Magnification

A drawing of a cell is 45 mm long, and the real cell is 0.15 mm long:

\text{magnification}=\frac{\text{image size}}{\text{actual size}}=\frac{45}{0.15}=\times300

Extended candidates may need to convert: 0.15 mm is 150 μm, because each millimetre is a thousand micrometres.

Osmosis: percentage change in mass

A potato cylinder goes from 3.20 g to 2.88 g in a sugar solution. The percentage change is (2.88 − 3.20) ÷ 3.20 × 100 = −10%. It lost water by osmosis, so the solution had a lower water potential than the potato cells.

Monohybrid inheritance

Two pea plants both carry one allele for tall (T) and one for short (t). A Punnett square gives TT, Tt, Tt and tt, so the ratio of tall to short offspring is 3 : 1, and the probability of a short plant is 1 in 4.

Work out the odds of a trait from a cross in our Genetics & DNA course, then press Mark to check your answer in the course:

Type the chance that a child of a random cross has a given trait.

Press Mark to have your answer marked in the Genetics & DNA course.

Use the daily paper as a short timed mock

Uni-Sine publishes a free daily paper for IGCSE Biology (Core) and IGCSE Biology (Extended). Each is a short timed mock: 8 questions worth 25 to 35 marks, with a suggested 30 to 40 minutes, marked when you finish. It is not a full Cambridge paper, and the questions are original, not past papers.

  • What it covers well: cells, microscopy and transport, enzymes and digestion, photosynthesis, respiration, the heart and circulation, diseases and immunity, the nervous system and hormones, inheritance and evolution, and ecology.
  • What it does not cover: the experimental skills of Paper 5 and Paper 6 and the multiple choice format of Papers 1 and 2. Classification, transport in plants, reproduction, excretion and biotechnology get less attention than on the real papers.

For full papers under exam conditions, use Cambridge past papers from your teacher, and read our IGCSE mocks guide for when mocks happen and how to revise for them.

Common mistakes in IGCSE Biology

  • Mixing up the units in magnification. Put image and actual size in the same unit first.
  • Saying "water concentration". Describe osmosis with water potential, or with solute concentration, as the mark scheme expects.
  • Writing genotypes loosely. Show the parents' alleles, the gametes and the Punnett square.
  • Not using the data. When a question gives a graph, quote numbers from it in your answer.

Common questions

What is the difference between Core and Extended IGCSE Biology?
Core covers the Core content and allows grades C to G. Extended adds the Supplement content and allows A* to G, with different multiple choice and theory papers.
When is the IGCSE Biology exam in 2027?
In Cambridge's June 2027 zone 3 timetable, the theory papers are on Monday 26 April, the practical papers on Tuesday 11 May and the multiple choice papers on Tuesday 8 June, all in the afternoon.
What were the IGCSE Biology grade thresholds in June 2026?
For Extended candidates sitting papers 21, 41 and 61, the thresholds out of 200 were 166 for A*, 138 for A and 83 for C. Other paper versions had different thresholds.
How many topics are in IGCSE Biology?
Twenty-one, from characteristics and classification of living organisms to biotechnology and genetic modification.
What is Paper 6 in IGCSE Biology?
The Alternative to Practical: a 1-hour written paper worth 40 marks and 20%, testing the same experimental skills as the Paper 5 practical test.

Revision cards

Say the answer first, then flip the card to check it.

Where to go next

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    IGCSE Biology (Core)

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