SACE Biology: DNA and proteins, cells, homeostasis and evolution
Year 11 Biology
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What the four topics ask of you
| Topic | Focus in the outline |
|---|---|
| 1. DNA and proteins | DNA structure and replication, gene expression, protein roles, mutation and the ethics of gene modification |
| 2. Cells as the basis of life | Cell theory, the fluid mosaic membrane, exchange of materials, binary fission and mitosis, culturing cells, and how cells evolved |
| 3. Homeostasis | Tolerance limits, the stimulus-response model, negative feedback, and how the nervous, endocrine and excretory systems regulate temperature, blood glucose, carbon dioxide and water balance |
| 4. Evolution | Evidence for evolution, gene pool diversity, natural selection, speciation and models for populations |
The outline names its own skills too: biologists use pathway and flow diagrams in Topic 3, and mathematical models of gene pools in Topic 4. Our Cell Biology course and Human Physiology course cover the basics of Topics 2 and 3.
The 70/30 split and the exam
The SACE Board sets the school assessment at 70%: an Investigations Folio worth 30% (one or two practical investigations and one investigation with a science as a human endeavour focus) and Skills and Applications Tasks worth 40% (three or four tasks). The external examination is Assessment Type 3, 30%, and lasts 130 minutes.
The outline says that questions may be of different types, may need an understanding of science as a human endeavour, and may ask you to apply understanding from more than one topic. All the assessment design criteria can be assessed in the exam, so expect data interpretation and experimental design questions alongside recall.
Worked examples
Why cells stay small
A cube-shaped cell with sides of 2 μm has a surface area of 6 × 2² = 24 μm² and a volume of 2³ = 8 μm³, so the surface area to volume ratio is 3. A cube with sides of 4 μm has a surface area of 96 μm² and a volume of 64 μm³, so the ratio is 1.5. Doubling the side halves the ratio, which means the cell has less membrane for every unit of cytoplasm to supply, and this is why large cells struggle to exchange materials fast enough.
Check a similar calculation in the Cell Biology course, then press Mark:
Work out the surface area, volume or surface area to volume ratio of a cube-shaped cell.
Press Mark to have your answer marked in the Cell Biology course.
Template to mRNA to protein
A template DNA strand reads 3′ TAC GGT CAT 5′. Transcription gives mRNA 5′ AUG CCA GUA 3′ (A pairs with U in RNA, and the strands run in opposite directions). The three codons then code for methionine, proline and valine in that order. Marks come from the base pairing rule, the direction, and naming which molecule you are describing at each step.
Negative feedback
If blood glucose rises after a meal, receptors detect the change, the pancreas releases insulin, cells take up glucose and the level falls. When the level returns to the set point, insulin release drops. Use the stimulus-response words the outline uses: stimulus, receptor, control centre, effector, response.
Grades, SATAC and your ATAR
The final result is reported from A+ to E−. SATAC turns the school and exam results into a raw score out of 15, with the school part contributing up to 10.5 and the exam part up to 4.5, then scales it before building the university aggregate from 90 credits of Stage 2 study. Biology is a 20-credit subject, so it can be one of the three subjects that count in the first 60 credits.
Dates
| Year | Biology exam | Notes |
|---|---|---|
| 2026 | Friday 6 November | 130 minutes; code 2BGY20 |
| 2027 | Not yet published | Check the SACE Board timetable |
Use the daily paper as a trial
Your school sets trial exams in South Australia, and the Board publishes past papers on the subject page. The free daily paper on the Year 12 Biology track is a short timed trial of 8 questions worth 25 to 35 marks, marked as you go. It is not a full 130-minute exam.
- It fits well: gene expression, mutation, evolution and speciation, homeostasis, hormones and nervous control are in its rotation and in the outline.
- It does not fit: muscle contraction, the kidney in detail, gene technology steps and Hardy-Weinberg are not named in Stage 2, and the paper cannot test the human endeavour and investigation parts of the exam.
- The Year 11 Biology paper revises cell structure and transport before Topic 2.
Exam answers
Answers and a worked mark scheme come with each daily paper once it has been marked. They are Uni-Sine's own, not official SACE Board answers.
Mistakes in SACE Biology
- Mixing up the template strand and the coding strand when writing mRNA.
- Describing negative feedback as the body "turning off" a response without naming the receptor and effector.
- Using "evolve" for a single organism.
- Giving a ratio without units or a comparison, when the question says "explain".
Common questions
What are the four topics in SACE Stage 2 Biology?
How long is the SACE Biology exam?
How is the school part assessed?
What is the grade scale?
Can the exam ask about science as a human endeavour?
Revision cards
Say it first, then flip.
Where to go next
- Solve it
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Cell Biology
The fundamental unit of life: organelles, membranes and how cells work
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Year 11 Biology
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